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METABOLIC EFFECTS OF BETA-SYMPATHOMIMETIC DRUGS AND DEXAMETHASONE IN NORMAL AND DIABETIC PREGNANCY
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1978.tb10478.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 85, Issue 3, pages 184–189, March 1978
Additional Information
How to Cite
Borberg, C., Gillmer, M. D. G., Beard, R. W. and Oakley, N. W. (1978), METABOLIC EFFECTS OF BETA-SYMPATHOMIMETIC DRUGS AND DEXAMETHASONE IN NORMAL AND DIABETIC PREGNANCY. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 184–189. doi: 10.1111/j.1471-0528.1978.tb10478.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Marked hyperglycaemia and hyperinsulinaemia were observed in two normal women in premature labour treated with an intravenous infusion of a β-sympathomimetic drug and intramuscular dexamethasone injections. Similar therapy in a chemical diabetic patient caused diabetic ketoacidosis, while treatment of an insulin dependent diabetic with dexamethasone alone resulted in a major increase in her insulin requirements. It is suggested that the diabetogenic effects of β-sympathomimetic drugs and dexamethasone may be additive and that regular plasma glucose estimations should be made when they are used, especially in patients with impaired glucose tolerance.