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THE SIGNIFICANCE OF A LOW AMNIOTIC FLUID CREATININE AND A MATURE LECITHIN/SPHINGOMYELIN RATIO
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1978.tb10481.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 85, Issue 3, pages 201–203, March 1978
Additional Information
How to Cite
Jenkins, D. T. and Wishart, M. M. (1978), THE SIGNIFICANCE OF A LOW AMNIOTIC FLUID CREATININE AND A MATURE LECITHIN/SPHINGOMYELIN RATIO. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 201–203. doi: 10.1111/j.1471-0528.1978.tb10481.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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Summary
Creatinine levels were measured in 546 specimens of amniotic fluid with a lecithin/ sphingomyelin ratio of 2.5 or more. With amniotic fluid creatinine levels below the normal range, 3 of 6 infants had major congenital abnormalities and two had severe rhesus isoimmunization; 3 of the infants died. Of 514 cases with amniotic fluid creatinine levels within the normal range (mean±2 SD), 13 babies (2.5 per cent) had major congenital abnormalities but only one of the babies died, giving a perinatal mortality rate of 0.2 per cent. The significance of these findings is discussed.