Queen charlotte's Maternity Hospital, London.
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CIRCULATING LEVELS OF ALPHA-FETOPROTEIN AND PREGNANCY SPECIFIC β1 GLYCOPROTEIN IN PREGNANCIES WITHOUT AN EMBRYO
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1978.tb14892.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 85, Issue 5, pages 348–350, May 1978
Additional Information
How to Cite
Bennett, M. J., Grudzinskas, J. G., Gordon, Y. B. and Turnbull, A. C. (1978), CIRCULATING LEVELS OF ALPHA-FETOPROTEIN AND PREGNANCY SPECIFIC β1 GLYCOPROTEIN IN PREGNANCIES WITHOUT AN EMBRYO. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 348–350. doi: 10.1111/j.1471-0528.1978.tb14892.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Ten patients with depressed serum alpha-fetoprotein (AFP) levels at 14 to 15 weeks gestation were found to have no embryo on ultrasonography: two patients had hydatidiform moles and the remainder had anembryonic pregnancies (blighted ova). The pregnancy specific β1 glycoprotein (SP1) levels in serum were measured in all these ten patients. Seven of the eight patients with anembryonic pregnancies and one of the two patients with molar pregnancies had low serum SP1, levels. These observations suggest that the measurement of AFP and SP1 may provide biochemical evidence of pregnancy without an embryo.