A STUDY OF THE EFFECTIVENESS OF PROPRANOLOL IN MENOPAUSAL HOT FLUSHES

  1. Jean Coope General Practitioner1,
  2. Susan Williams Student1,
  3. J. S. Patterson Medical Adviser2

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1978.tb14916.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 85, Issue 6, pages 472–475, June 1978

Additional Information

How to Cite

Coope, J., Williams, S. and Patterson, J. S. (1978), A STUDY OF THE EFFECTIVENESS OF PROPRANOLOL IN MENOPAUSAL HOT FLUSHES. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 472–475. doi: 10.1111/j.1471-0528.1978.tb14916.x

Author Information

  1. 1

    Bollington Group Practice, Bollington, Cheshire

  2. 2

    Clinical Research Department, ICI Pharmaceuticals Division, Mereside Alderley Park, Macclesfield, Cheshire

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005

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Summary

A prospective, double-blind, randomized comparison of propranolol, 40 mg three times daily, and matching placebo showed propranolol to be no more effective than placebo in controlling hot flushes in a group of 25 perimenopausal women. Other menopausal symptoms, such as insomnia and palpitations, were equally unaffected. However, a very close correlation was found between the daily atmospheric temperature and the number of flushes occurring in the group.

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