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SEX HORMONE LEVELS AND GONADOTROPHIN RELEASE IN PREMATURE OVARIAN FAILURE
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1978.tb15844.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 85, Issue 11, pages 862–867, November 1978
Additional Information
How to Cite
Duignan, N. M., Shaw, R. W., Glass, M. R., Butt, W. R. and Edwards, R. L. (1978), SEX HORMONE LEVELS AND GONADOTROPHIN RELEASE IN PREMATURE OVARIAN FAILURE. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 862–867. doi: 10.1111/j.1471-0528.1978.tb15844.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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- Cited By
Summary
Premature ovarian failure was studied in ten women under the age of 30; eight had an ovarian biopsy and five of these showed primordial follicles. Plasma levels of oestradiol and progesterone were similar to the follicular phase of a normal menetrual cycle, but in eight patients cervical smears showed a cornification index of less than one per cent. Levels of both androgens and of sex hormone binding globulin capacity were generally normal. Administration of LH-RH caused a release of FSH which was similar to post menopausal women and higher than normally menstruating women, and a release of LH which was higher than both. Two patients were treated with exogenous gonadotrophins without effect.