T. C. D. Unit, Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1.
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SECRETION PATTERNS OF PLASMA-PROGESTERONE, 17-HYDROXYPROGESTERONE, AND 20α HYDROXYPREGN-4-EN-3-ONE IN EARLY ABNORMAL PREGNANCY
Article first published online: 31 AUG 2005
DOI: 10.1111/j.1471-0528.1978.tb15855.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 85, Issue 12, pages 927–932, December 1978
Additional Information
How to Cite
Harrison, R. F., Youssefnejadian, E., Brodovcky, H., Johnson, M. and Dewhurst, J. (1978), SECRETION PATTERNS OF PLASMA-PROGESTERONE, 17-HYDROXYPROGESTERONE, AND 20α HYDROXYPREGN-4-EN-3-ONE IN EARLY ABNORMAL PREGNANCY. BJOG: An International Journal of Obstetrics & Gynaecology, 85: 927–932. doi: 10.1111/j.1471-0528.1978.tb15855.x
Publication History
- Issue published online: 31 AUG 2005
- Article first published online: 31 AUG 2005
- Abstract
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Summary
Plasma progesterone, 17-hydroxyprogesterone, 20α hydroxypregn-4-en-3-one levels were determined twice weekly up to 16 weeks gestation, where possible, in a twin pregnancy, in two patients who aborted spontaneously and in three patients who were treated with‘progesterone supplements’because of abnormal vaginal cytology. There was no correlation between vaginal smears and the plasma hormone levels and there was no evidence to suggest that progesterone supplements influenced clinical outcome. Compared with normal mean values the only difference was a significant rise in progesterone and 20a hydroxypregn-4-en-3-one levels in the twin pregnancy after the 12th week and a precipitate fall in all hormone levels just prior to abortion. Plasma hormone levels could not be used to predict outcome.