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ACUTE MENOPAUSAL TRANSITION ASSOCIATED WITH CLOMIPHENE THERAPY: TWO CASE REPORTS
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1979.tb10600.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 86, Issue 3, pages 238–242, March 1979
Additional Information
How to Cite
Lenton, E. A., Burton, R. M. and Cooke, I. D. (1979), ACUTE MENOPAUSAL TRANSITION ASSOCIATED WITH CLOMIPHENE THERAPY: TWO CASE REPORTS. BJOG: An International Journal of Obstetrics & Gynaecology, 86: 238–242. doi: 10.1111/j.1471-0528.1979.tb10600.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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Summary
Two patients presenting with anovulation and secondary infertility were treated with clomiphene citrate. Intermittent blood samples were obtained for the first three months of therapy in each case. One patient failed either to ovulate or menstruate in response to clomiphene and the other patient had only two episodes of cyclical bleeding before she too became amenorrhoeic. Hormonal analyses revealed that both women had undergone a rapid and precocious menopausal transition which has persisted throughout the subsequent three years.