Present address: Department of Obstetrics and Gynaecology, University of Leiden, Medical Centre, Rijnsburgerweg 10, Leiden, The Netherlands.
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CONCENTRATIONS OF THE PROSTACYCLIN METABOLITE, 6–KETO–PROSTAGLANDIN F1α, IN AMNIOTIC FLUID DURING LATE PREGNANCY AND LABOUR.
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1979.tb10609.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 86, Issue 5, pages 350–353, May 1979
Additional Information
How to Cite
Mitchell, M. D., Keirse, M. J. N. C., Brunt, J. D., Anderson, A. B. M. and Turnbull, A. C. (1979), CONCENTRATIONS OF THE PROSTACYCLIN METABOLITE, 6–KETO–PROSTAGLANDIN F1α, IN AMNIOTIC FLUID DURING LATE PREGNANCY AND LABOUR.BJOG: An International Journal of Obstetrics & Gynaecology, 86: 350–353. doi: 10.1111/j.1471-0528.1979.tb10609.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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Summary
Concentrations of 6–keto–prostaglandin F1α (6–keto–PGF1α, the stable metabolite of prostacyclin, PGI2) have been measured in amniotic fluid obtained during late pregnancy and labour. Samples taken at amniotomy during spontaneous labour contained a significantly greater concentration of 6–keto–PGF1α than samples taken at amniotomy before the onset of labour (p <0.01). There was no correlation between the level of 6–keto–PGF1α, in amniotic fluid before labour and gestational age (p > 0 1). It is suggested that prostacyclin may have a functional role in the mechanism of parturition in man.