Department of Obstetrics and Gynaecology, Markusovszky Teaching Hospital, Szom- bathely, Hungary.
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POLYAMINE OXIDASE ACTIVITY IN HUMAN PREGNANCY SERUM
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1979.tb10715.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 86, Issue 11, pages 878–881, November 1979
Additional Information
How to Cite
Illei, G. and Morgan, D. M. L. (1979), POLYAMINE OXIDASE ACTIVITY IN HUMAN PREGNANCY SERUM. BJOG: An International Journal of Obstetrics & Gynaecology, 86: 878–881. doi: 10.1111/j.1471-0528.1979.tb10715.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
The existence of a spermine oxidizing enzyme was established in human pregnancy serum by a radiochemical method, and a cross-sectional study of its quantitative profile between 10 and 40 weeks gestation was undertaken. Though there was a wide scatter of values, the rise in the average activity was continuous and highly significant. The flavoprotein inhibitor, quinacrin, inhibited the enzyme activity, while the pyridoxal phosphate inhibitor, isoniazid, had no significant inhibitory effect suggesting that the enzyme is of tissue origin. The possible role of polyamines and their oxidation in physiological immunoregulation is discussed.