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Summary

It is likely that there are systematic differences between circulating pregnancy-specific β1 glycoprotein (SP1) levels measured by radioimmunoassay and immunoprecipitation systems. We have re-investigated the decline in circulating levels of SP1 following delivery of the placenta. Serial blood samples were collected for 120 hours from 10 women following Caesarean section or vaginal delivery at term. The apparent half-life of SP1 after delivery ranged between 17 and 45 hours.