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CHANGES IN COAGULATION FACTORS IN POSTMENOPAUSAL WOMEN ON ETHINYL OESTRADIOL
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1979.tb10795.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 86, Issue 6, pages 488–490, June 1979
Additional Information
How to Cite
Hunter, D. J. S., Anderson, A. B. M. and Haddon, M. (1979), CHANGES IN COAGULATION FACTORS IN POSTMENOPAUSAL WOMEN ON ETHINYL OESTRADIOL. BJOG: An International Journal of Obstetrics & Gynaecology, 86: 488–490. doi: 10.1111/j.1471-0528.1979.tb10795.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
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Summary
Coagulation factors II, VII, X, VII X complex and anti-thrombin III were measured in 10 postmenopausal women before, during and after a four-month course of 20 μg daily of ethinyl oestradiol, taken three weeks in four. Factors VII, X and VII X complex rose significantly during treatment but only factor X levels were significantly elevated at the end of the four-month treatment period. There was no change in factor II or anti-thrombin III levels. These effects on coagulation factors during ethinyl oestradiol therapy are, in general, similar to those found during treatment with conjugated equine oestrogens and oestradiol valerate in a previous study from the same laboratory. It seems likely that equipotent doses of ethinyl oestradiol and‘natural’oestrogens have similar effects on these coagulation factors.