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AMNIOTIC FLUID PALMITIC ACID/STEARIC ACID RATIOS, LECITHIN/SPHINGOMYELIN RATIOS AND PALMITIC ACID CONCENTRATIONS IN THE ASSESSMENT OF FETAL LUNG MATURITY IN DIABETIC PREGNANCIES
Article first published online: 31 AUG 2005
DOI: 10.1111/j.1471-0528.1979.tb11244.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 86, Issue 12, pages 959–964, December 1979
Additional Information
How to Cite
Anderws, A. G., Brown, J. B., Jeffery, P. E. and Horacek, I. (1979), AMNIOTIC FLUID PALMITIC ACID/STEARIC ACID RATIOS, LECITHIN/SPHINGOMYELIN RATIOS AND PALMITIC ACID CONCENTRATIONS IN THE ASSESSMENT OF FETAL LUNG MATURITY IN DIABETIC PREGNANCIES. BJOG: An International Journal of Obstetrics & Gynaecology, 86: 959–964. doi: 10.1111/j.1471-0528.1979.tb11244.x
Publication History
- Issue published online: 31 AUG 2005
- Article first published online: 31 AUG 2005
- Abstract
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Summary
The lecithin/sphingomyelin (L/S) ratio, palmitic acid concentration and palmitic to stearic acid (P/S) ratio were estimated on samples of amniotic fluid obtained from 66 patients with diabetes. These were compared with similar estimates on amniotic fluid obtained from 127 non-diabetic patients. At 35 to 40 weeks, significant differences were observed between the L/S ratio and palmitic acid concentration in diabetics and non-diabetics, whereas the P/S ratio was similar in the two groups. The amniotic fluid L/S ratio, palmitic acid concentration, and P/S ratio were estimated on amniotic fluid obtained from 20 diabetic patients within 48 hours of induction, and the clinical outcome of the newborn infant was used to assess the predictive value of the three parameters. In 19 out of the 20 diabetics the P/S ratio correctly predicted fetal lung maturity, whereas the palmitic acid concentration was correct in 12 patients and the L/S ratio in only 10 patients.