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A DOUBLE-BLIND TRIAL OF SINGLE-DOSE CHEMOPROPHYLAXIS WITH CO-TRIMOXAZOLE DURING VAGINAL HYSTERECTOMY AND REPAIR
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1979.tb11277.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 86, Issue 9, pages 737–740, September 1979
Additional Information
How to Cite
Mathews, D. D., Agarwal, V., Gordon, A. M. and Cooper, J. (1979), A DOUBLE-BLIND TRIAL OF SINGLE-DOSE CHEMOPROPHYLAXIS WITH CO-TRIMOXAZOLE DURING VAGINAL HYSTERECTOMY AND REPAIR. BJOG: An International Journal of Obstetrics & Gynaecology, 86: 737–740. doi: 10.1111/j.1471-0528.1979.tb11277.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary
Twenty-five patients received 10 ml co-trimoxazole (800 mg sulphamethoxazole and 160 mg trimethoprim) and 25 a placebo by intravenous infusion during one hour from the commencement of surgery for vaginal hysterectomy with anterior colporrhaphy and posterior colpo-perineorrhaphy. Single-dose chemoprophylaxis with co-trimoxazole was shown to be effective in reducing the incidence of post-operative febrile morbidity and urinary tract infection, especially that caused by Proteus species.