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IMPROVED DIAGNOSIS OF PREGNANCY-RELATED GYNAECOLOGICAL EMERGENCIES BY RAPID HUMAN CHORIONIC GONADOTROPHIN BETA-SUBUNIT ASSAY
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb00957.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 2, pages 138–140, February 1981
Additional Information
How to Cite
Seppälä, M., Ranta, T., Rutanen, E.-M., Stenman, U.-H., Tontti, K. and Chard, T. (1981), IMPROVED DIAGNOSIS OF PREGNANCY-RELATED GYNAECOLOGICAL EMERGENCIES BY RAPID HUMAN CHORIONIC GONADOTROPHIN BETA-SUBUNIT ASSAY. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 138–140. doi: 10.1111/j.1471-0528.1981.tb00957.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received June 23, 1980/Accepted August 26, 1980
- Abstract
- References
- Cited By
Summary
A pregnancy-related disorder was identified by a rapid radioimmunoassay of serum chorionic gonadotrophin (hCG-RIA) in 122 out of 470 women (26 per cent) with lower abdominal pain or bleeding, while a routine pregnancy test in urine was positive in only 7 per cent of these cases. In 49 patients with ectopic pregnancy the rapid hCG-RIA was positive in 90 per cent as compared with 13 per cent for the routine pregnancy test. In patients with evidence of intrauterine pregnancy (66 cases) the rapid hCG-RIA was positive in 98 per cent and the routine pregnancy test in 38 per cent. The clinical sensitivity of the hCG-RIA was 95 per cent, specificity 96 per cent and predictive value 89 per cent. The test can improve the efficiency of the routine diagnosis of early intra- and extrauterine pregnancy-related disorders.