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IMMUNOPATHOLOGICAL AND CLINICAL STUDIES IN HERPES GESTATIONIS
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb00961.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 2, pages 153–159, February 1981
Additional Information
How to Cite
Foidart, J. M., Yaar, M., Hall, R., Gaspard, U. and Katz, S. I. (1981), IMMUNOPATHOLOGICAL AND CLINICAL STUDIES IN HERPES GESTATIONIS. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 153–159. doi: 10.1111/j.1471-0528.1981.tb00961.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received April 22, 1980/Accepted August 5, 1980
- Abstract
- References
- Cited By
Summary
Herpes gestationis is a recurring pruritic, vesiculobullous disease of pregnancy and puerperium. Recently, Lawley et al (1979) reported a high frequency (38 per cent) of fetal morbidity and mortality in 40 cases of immunologically proven herpes gestationis. This study was undertaken to determine whether the antibody to skin basement membrane (found in most patients with herpes gestationis) is able to bind to the placenta basement membranes and thereby to threaten the pregnancy. We were unable to detect this antibody in the placental basement membranes of a patient with herpes gestationis, nor could we demonstrate that the anti-basement membrane antibody, found in the sera of herpes gestationis patients, binds to homologous or autologous placentas and fetal membranes. The importance of an accurate diagnosis and appropriate treatment of this condition is discussed.