PROSTAGLANDIN E AND F CONCENTRATIONS IN PLACENTAE OF NORMAL, HYPERTENSIVE AND PRE-ECLAMPTIC PATIENTS
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb00981.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 3, pages 274–277, March 1981
Additional Information
How to Cite
Hillier, K. and Smith, M. D. (1981), PROSTAGLANDIN E AND F CONCENTRATIONS IN PLACENTAE OF NORMAL, HYPERTENSIVE AND PRE-ECLAMPTIC PATIENTS. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 274–277. doi: 10.1111/j.1471-0528.1981.tb00981.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received March 3, 1980/Accepted November 11, 1980
- Abstract
- References
- Cited By
Summary
The prostaglandins E and F were measured by radioimmunoassay in placentae from 23 normotensive, 25 hypertensive and 13 pre-eclamptic patients. The prostaglandin E levels were respectively (pg/mg±SEM) 16.34±2.06, 16±75.2±52 and 12±10.3±63. The prostaglandin F levels were 2.43±0.41, 2.70±0–42 and 2.06±0.31. These prostaglandin concentrations did not differ significantly. Local ischaemia may, therefore, be explained by altered responsiveness to these prostaglandins or to changes in other prostaglandins (such as the vasodilator PGI2) or other vasoactive agents.

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