A COMPARISON OF PLASMA PROSTAGLANDIN LEVELS IN TERM AND PRETERM LABOUR

  1. Susan M. Sellers,
  2. M. D. Mitchell,
  3. J. G. Bibby,
  4. Anne B. M. Anderson,
  5. A. C. Turnbull

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1981.tb00997.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 88, Issue 4, pages 362–366, April 1981

Additional Information

How to Cite

Sellers, S. M., Mitchell, M. D., Bibby, J. G., Anderson, A. B. M. and Turnbull, A. C. (1981), A COMPARISON OF PLASMA PROSTAGLANDIN LEVELS IN TERM AND PRETERM LABOUR. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 362–366. doi: 10.1111/j.1471-0528.1981.tb00997.x

Author Information

  1. Nuffield Department of Obstetrics and Gynaecology, University of Oxford John Radcliffe Hospital, Headington, Oxford, OX3 9DU

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received August 13, 1980/Accepted November 11, 1980

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Summary

Peripheral plasma levels of 13,14-dihydro-15-keto-prostaglandin F (PGFM) were determined in women during pregnancy and in term and preterm labour. The PGFM concentrations at term were not significantly different from the levels between 26 and 34 weeks gestation. In both term and preterm labour there was a rise in PGFM levels with increasing cervical dilatation although the mean values tended to be lower during preterm labour. These findings may provide an explanation for the effectiveness of prostaglandin synthetase inhibitors in suppressing myometrial activity in preterm labour.

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