Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, Texas 75235, U. S. A.
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THE RELATION BETWEEN THE RELEASE OF PROSTAGLANDINS AT AMNIOTOMY AND THE SUBSEQUENT ONSET OF LABOUR
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb01199.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 12, pages 1211–1216, December 1981
Additional Information
How to Cite
Sellers, S. M., Mitchell, M. D., Anderson, A. B. M. and Turnbull, A. C. (1981), THE RELATION BETWEEN THE RELEASE OF PROSTAGLANDINS AT AMNIOTOMY AND THE SUBSEQUENT ONSET OF LABOUR. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 1211–1216. doi: 10.1111/j.1471-0528.1981.tb01199.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received June 26, 1981/Accepted August 25, 1981
- Abstract
- References
- Cited By
Summary
Maternal peripheral plasma levels of 13,14-dihydro-15-keto-prostaglandin F (PGFM) were measured in 16 women following amniotomy performed for the induction of labour at term. After 5½ hours, seven patients were in established labour (Group I) but the remaining nine patients required an intravenous infusion of oxytocin (Group II). An initial rapid rise in PGFM concentrations within five minutes of amniotomy occurred in all women and, therefore, the onset of labour does not appear to be a direct consequence of this initial increase. In Group I there was a significant increase in PGFM concentrations between five and 30 minutes after amniotomy and from 30 minutes to the time at which the last sample was collected; these later rises were associated with the onset and progress of labour in these women. These increases in PGFM concentrations did not occur in patients in Group II. The reason for this difference in response to amniotomy is as yet unclear.