A DOUBLE BLIND TRIAL OF EXTRA-AMNIOTIC OESTRIOL AND PROSTAGLANDIN F2α GELS IN CERVICAL RIPENING

  1. M. A. Quinn Senior Registrar†,
  2. A. Jmurphy Registrar,
  3. R. J. P. Kuhn Second Assistent,
  4. H. P. Robinson First Assistant,
  5. J. B. Brown Professor

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1981.tb01223.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 88, Issue 6, pages 644–649, June 1981

Additional Information

How to Cite

Quinn, M. A., Jmurphy, A., Kuhn, R. J. P., Robinson, H. P. and Brown, J. B. (1981), A DOUBLE BLIND TRIAL OF EXTRA-AMNIOTIC OESTRIOL AND PROSTAGLANDIN F2α GELS IN CERVICAL RIPENING. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 644–649. doi: 10.1111/j.1471-0528.1981.tb01223.x

Author Information

  1. Royal Wamen's Hospital and Department of Obstetrics and Gynaecology University of Melbourne

  1. †

    Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, Nova Scotia, Canada.

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received October 14, 1980/Accepted December 12, 1980.

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Summary

Forty nulliparous patients with a Bishop score of 3 or less were given 15 mg oestriol gel, 10 mg PGF2α gel or gel alone via the extra-amniotic route. Both the oestriol and prostaglandin treated patients had a significant increase in Bishop score and a significant reduction in induction-delivery interval compared to con-trols. Oestriol gel had significantly less stimulatory effect on uterine activity than prostaglandin gel, indicating a possible local action.

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