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COMPARISON OF EPIDURAL AND INTRAMUSCULAR PETHIDINE FOR ANALGESIA IN LABOUR
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb01270.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 7, pages 711–717, July 1981
Additional Information
How to Cite
Husemeyer, R. P., Davenport, H. T., Cummings, A. J. and Rosankiewicz, J. R. (1981), COMPARISON OF EPIDURAL AND INTRAMUSCULAR PETHIDINE FOR ANALGESIA IN LABOUR. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 711–717. doi: 10.1111/j.1471-0528.1981.tb01270.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received December 12, 1980/Accepted January 21, 1981.
- Abstract
- References
- Cited By
Summary
Analgesia mediated by a direct spinal action of narcotic drugs administered via the epidural route may have considerable advantages over conventional (conduction block) epidural analgesia in labour. The efficacy, mode of action and placental transfer of epidurally administered narcotics in labour has not yet been established. We have compared the systemic absorption, analgesia and other effects on the mothers and transfer of drug to the fetus in primigravidae who received epidural or intramuscular pethidine 100 mg in labour. The superior analgesia following epidural pethidine did not appear to be attributable to a selective spinal action but rather to higher plasma concentrations of pethidine together with a possible weak regional conduction block due to local anaesthetic action of 1 % pethidine solution. Epidural pethidine is not an advantageous method for providing analgesia in labour.