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EFFECT OF TERBUTALINE ON THE HUMAN FETAL PLACENTAL CIRCULATION
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb01274.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 7, pages 730–733, July 1981
Additional Information
How to Cite
Scares de Moura, R. (1981), EFFECT OF TERBUTALINE ON THE HUMAN FETAL PLACENTAL CIRCULATION. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 730–733. doi: 10.1111/j.1471-0528.1981.tb01274.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received September 16, 1980/Accepted January 5, 1981.
- Abstract
- References
- Cited By
Summary
The effect of terbutaline, a β2-adrenoceptor stimulator, on the vascular resistance of isolated human placenta was examined. Terbutaline produced no change in basal placental vascular resistance, but when the placental vessels were constricted with angiotensin, terbutaline produced a graded decrease in vascular resistance. The vasodilating effect of a high dose of terbutaline was smaller than the effect of 20 μg of isoprenaline and the effect was significantly blocked by propranolol, a β-adreno-ceptor antagonist. The results suggest that the vasodilating effect of terbutaline on the fetal placental circulation can play a role in the improvement of fetal condition during treatment of premature labour and intrapartum fetal distress.