Present appointment: Senior Registrar in Community Medicine, Oxford Regional Health Authority.
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ORAL CONTRACEPTION AND MYOCARDIAL INFARCTION REVISITED: THE EFFECTS OF NEW PREPARATIONS AND PRESCRIBING PATTERNS
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb01311.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 8, pages 838–845, August 1981
Additional Information
How to Cite
Adam, S. A., Thorogood, M. and Mann, J. I. (1981), ORAL CONTRACEPTION AND MYOCARDIAL INFARCTION REVISITED: THE EFFECTS OF NEW PREPARATIONS AND PRESCRIBING PATTERNS. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 838–845. doi: 10.1111/j.1471-0528.1981.tb01311.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received January 16, 1981/Accepted March 4, 1981.
- Abstract
- References
- Cited By
Summary
All deaths from myocardial infarction occurring during 1978 in women aged 15–44 years in England and Wales have been investigated. Using a case-control approach, oral contraceptives were found to be associated with an approximately two-fold increase in risk of this condition, but the effect was apparent only in women with no known risk factors for ischaemic heart disease. Preparations containing 30 μg or less oestrogen were associated with the same risk as those containing 50 μg oestrogen, but this could be due to the fact that preparations containing less oestrogen tend to contain higher doses of progestogens. Oral contraceptives appear no longer to be prescribed for women with recognised coronary risk factors and this improved prescribing practice has probably resulted in a substantial decrease in mortality attributable to oral contraceptive use.