1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
TROPHOBLAST SAMPLING IN EARLY PREGNANCY. CULTURE OF RAPIDLY DIVIDING CELLS FROM IMMATURE PLACENTAL VILLI
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb01756.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 11, pages 1081–1085, November 1981
Additional Information
How to Cite
Niazi, M., Coleman, D. V. and Loeffler, F. E. (1981), TROPHOBLAST SAMPLING IN EARLY PREGNANCY. CULTURE OF RAPIDLY DIVIDING CELLS FROM IMMATURE PLACENTAL VILLI. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 1081–1085. doi: 10.1111/j.1471-0528.1981.tb01756.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received March 2, 1981/Accepted July 16, 1981
- Abstract
- References
- Cited By
Summary
Trophoblast was obtained by ordinary suction curettage and by transcervical aspiration with a medicut cannula from women having a therapeutic abortion in the first trimester of pregnancy. The decidual tissue which is invariably attached to early placental villi was separated and pure cultures obtained from the trophoblast layers and from the mesenchymal core of placental villi. Cytotrophoblast had a very limited life span in tissue culture, whereas mesenchymal cells grew rapidly and could be used for antenatal diagnosis.