1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
THE EFFECT OF PROGESTERONE, OESTROGENS AND HYDROCORTISONE ON THE MITOGENIC RESPONSE OF LYMPHOCYTES TO PHYTOHAEMAGGLUTININ IN PREGNANT AND NON-PREGNANT WOMEN
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1981.tb01763.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 88, Issue 11, pages 1110–1114, November 1981
Additional Information
How to Cite
Skinnider, L. F. and Laxdal, V. (1981), THE EFFECT OF PROGESTERONE, OESTROGENS AND HYDROCORTISONE ON THE MITOGENIC RESPONSE OF LYMPHOCYTES TO PHYTOHAEMAGGLUTININ IN PREGNANT AND NON-PREGNANT WOMEN. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 1110–1114. doi: 10.1111/j.1471-0528.1981.tb01763.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received May 12, 1981/Accepted July 1, 1981
- Abstract
- References
- Cited By
Summary
The mitogenic response to phytohaemagglutinin of lymphocytes from women in the third trimester of pregnancy is not inhibited by progesterone, oestriol or oestradiol even at much greater than normal physiological levels. There was no difference in the response of lymphocytes from pregnant or non-pregnant women. Inhibition in the mitogenic response to phytohaemagglutinin was achieved with hydrocortisone but not at the physiological levels found in pregnancy. The results from this in vitro study would not support the view that the level of steroid hormones in pregnancy significantly affects the immunological status of the mothers.