THE MANAGEMENT OF CHORIOCARCINOMA CAUSING SEVERE THYROTOXICOSIS

TWO CASE REPORTS

  1. W. P. Soutter1,†,
  2. R. Norman2,
  3. R. W. Green-Thompson3

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1981.tb02233.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 88, Issue 9, pages 938–943, September 1981

Additional Information

How to Cite

Soutter, W. P., Norman, R. and Green-Thompson, R. W. (1981), THE MANAGEMENT OF CHORIOCARCINOMA CAUSING SEVERE THYROTOXICOSIS. BJOG: An International Journal of Obstetrics & Gynaecology, 88: 938–943. doi: 10.1111/j.1471-0528.1981.tb02233.x

Author Information

  1. 1

    Department of Obstetrics and Gynaecology King Edward VIII Hospital, Durban, Republic of South Africa

  2. 2

    Medical Officer Department of Chemical Pathology University of Natal, Durban, Republic of South Africa

  3. 3

    Senior Lecturer Department of Obstetrics and Gynaecology University of Natal, King Edward VIII Hospital, Durban, Republic of South Africa

  1. †

    Senior Lecturer, Department of Obstetrics and Gynaecology, University of Sheffield, Jessop Hospital for Women, Sheffield S3 7RE.

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received July 21, 1980/Accepted April 3, 1981

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Summary

Two patients with metastatic choriocarcinoma complicated by severe thyrotoxicosis, leading to cardiac failure in one instance and thyroid crisis in the other, are described. The successful treatment of these complications is detailed, and routine prophylaxis for high risk patients, using propylthiouracil, oral iodide, propranolol and urgent, aggressive chemotherapy, is recommended.

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