Colposcopy in the diagnosis of papillomavirus infection of the uterine cervix

  1. P. G. WALKER1,2,
  2. A. SINGER2,
  3. J. L. DYSON3,
  4. K. V. SHAH4,
  5. J. WILTERS2,†,
  6. D. V. COLEMAN1

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1983.tb06448.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 90, Issue 11, pages 1082–1086, November 1983

Additional Information

How to Cite

WALKER, P. G., SINGER, A., DYSON, J. L., SHAH, K. V., WILTERS, J. and COLEMAN, D. V. (1983), Colposcopy in the diagnosis of papillomavirus infection of the uterine cervix. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 1082–1086. doi: 10.1111/j.1471-0528.1983.tb06448.x

Author Information

  1. 1

    Department of Pathology, St Mary's Hospital, Paddington, London

  2. 2

    Department of Gynaecology, Royal Northern Hospital, Holloway, London

  3. 3

    Department of Pathology, Royal Northern Hospital, Holloway, London

  4. 4

    Department of Immunology and Infectious Diseases, The John Hopkins University, Baltimore, USA

  1. †

    Department of Obstetrics and Gynecology, University of Alabama, Birmingham Medical Centre, Birmingham, Alabama 35294, USA.

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 14 February 1983 Accepted 10 April 1983

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Summary. Morphological criteria are described for the diagnosis of papillomavirus lesions at colposcopy. Using these criteria, evidence of cervical papillomavirus infection was found in 58 (29.0%) of 200 women referred for colposcopy because of an abnormal cytology report. Directed biopsies were obtained from 152 of these patients and histological changes suggestive of papillomavirus infection were found in 47 (30.9%); additional biopsy material from 139 was studied using an immunohisto-chemical technique and human papillomavirus antigen was demonstrated in 28 (20.1%). Comparison between the colposcopic results and those obtained by histology suggests that whereas it is not possible to make a distinction at colposcopy between lesions due to papillomavirus and those of cervical intraepithelial neoplasia, it is possible to identify those epithelial abnormalties that are most likely to be associated with a papillomavirus infection.

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