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Exclusion of the fetal brain as the main source of rat and human amniotic fluid oxytocin
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1983.tb06465.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 12, pages 1160–1167, December 1983
Additional Information
How to Cite
SWAAB, D. F. and OOSTERBAAN, H. P. (1983), Exclusion of the fetal brain as the main source of rat and human amniotic fluid oxytocin. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 1160–1167. doi: 10.1111/j.1471-0528.1983.tb06465.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Abstract
- References
- Cited By
Summary. At term relatively high oxytocin concentrations are found in maternal plasma and in rat and human amniotic fluid. To determine the contribution of the fetal brain to these oxytocin levels, the peptide was measured in maternal rat plasma and amniotic fluid 2 days after intrauterine removal of the fetal brains, and in the amniotic fluid of 16 human anencephalics. After removal of the fetal rat brains and in human anencephalic pregnancies normal maternal plasma concentrations and amniotic fluid oxytocin contents were found. Consequently, both maternal plasma oxytocin and amniotic fluid oxytocin are not determined to any substantial degree by the fetal brain.