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Some effects of maternal pethidine administration on the newborn
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1983.tb06742.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 1, pages 28–33, January 1983
Additional Information
How to Cite
ROOTH, G., LYSIKIEWICZ, A., HUCH, R. and HUGH, A. (1983), Some effects of maternal pethidine administration on the newborn. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 28–33. doi: 10.1111/j.1471-0528.1983.tb06742.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 3 March 1982 Accepted 25 June 1982
- Abstract
- References
- Cited By
Summary. The effects of maternal pethidine administration (100 mg itramuscularly) were investigated in 150 infants at 1–2 h after birth, 95 infants whose mothers had not received pethidine served as a control group. Pethidine administration showed no effect on pH or Pco2 of cord blood and neonatal arterial blood at 1–2 h after birth if the time interval between pethidine administration and delivery was ≤1 h. However, when the interval was >1 h: umbilical vein blood PCO2 was higher; neonatal arterial blood PCO2 was higher; neonatal baseline heart rate was higher, although long-term variability was similar; the percentage time spent crying was considerably reduced compared with the corresponding values in the control group. The long-term effects of pethidine are unknown but the adverse neonatal factors particularly if the time interval between administration of the drug and delivery is >1 h should be kept in mind.