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The influence of oral contraceptives on activated factor X inhibitor (XaI)-activity: a prospective study
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1983.tb06769.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 10, pages 953–957, October 1983
Additional Information
How to Cite
BERGQVIST, A., BERGQVIST, D. and TANGEN, O. (1983), The influence of oral contraceptives on activated factor X inhibitor (XaI)-activity: a prospective study. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 953–957. doi: 10.1111/j.1471-0528.1983.tb06769.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 22 December 1982 Accepted 5 April 1983
- Abstract
- References
- Cited By
Summary. A prospective study of activated factor X inhibitor (XaI) activity has been performed in women randomly allocated to contraceptive pills containing 30μg+150μg (63 women) or 50μg+250μg (44 women) ethinyl oestradiol and levonorgestrel, and a reference group of 35 women using other contraceptive methods. The XaI-activity was measured six times during 1 year of observation. There was a significant reduction of XaI-activity after 1 month of oestrogen consumption but there was no significant difference between 30 and 50 μg users. The maximal reduction during the observation period was 12% in both groups. There was positive correlation between the pretreatment value and the maximal reduction in the same patient, but the activity did not fall below the normal range (75–125% of normal human plasma).