Increased decidual prostaglandin E concentration in human abortion

  1. OSCAR E. JASCHEVATZKY Consultant1,
  2. AMOS SHALIT Consultant1,
  3. STEPHAN GRUNSTEIN Director1,
  4. JACOB KAPLANSKI Senior Lecturer2,
  5. ABRAHAM DANON Associate Professor2

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1983.tb06770.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 90, Issue 10, pages 958–960, October 1983

Additional Information

How to Cite

JASCHEVATZKY, O. E., SHALIT, A., GRUNSTEIN, S., KAPLANSKI, J. and DANON, A. (1983), Increased decidual prostaglandin E concentration in human abortion. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 958–960. doi: 10.1111/j.1471-0528.1983.tb06770.x

Author Information

  1. 1

    Department of Obstetrics and Gynaecology, Hillel Jaffe Memorial Hospital, 38101 Hadera

  2. 2

    Clinical Pharmacology Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 24 August 1982 Accepted 4 April 198 3

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Summary. Prostaglandin E (PGE) concentration was measured in decidual tissue after spontaneous and missed abortion and compared with that obtained from induced abortion. Tissues were obtained by curettage from groups of 10 patients each and PGE was estimated by radioimmunoassay. After spontaneous and missed abortions decidual tissue contained significantly higher mean concentrations of PGE, (486.3 and 66.7 ng/g wet tissue respectively) than after induced abortion (18.6 ng PGE/g wet tissue). It is suggested that an increased rate of PGE biosynthesis or reduced breakdown, or both, may play a role in the mechanism of human abortion.

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