Senior Registrar, Department of Obstetrics, John Radcliffe Hospital, Headington, Oxford.
Pregnancy in sickle cell disease in the UK
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1983.tb08893.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 2, pages 112–117, February 1983
Additional Information
How to Cite
TUCK, S. M., STUDD, J. W. W. and WHITE, J. M. (1983), Pregnancy in sickle cell disease in the UK. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 112–117. doi: 10.1111/j.1471-0528.1983.tb08893.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 19 March 1982 Accepted August 10 1982
- Abstract
- References
- Cited By
Summary. The complications and outcome of 125 pregnancies in women with sickle cell disease between 1975 and 1981 are reviewed. There were no maternal deaths, but a perinatal mortality rate of 48 per 1000. The main maternal complications were sickling crises (38%), anaemia (65%), infections (61%) and severe pregnancy-induced hypertensive disease (5%). There were three patients with eclampsia. There was a 13% spontaneous preterm delivery rate, 25% of the babies were‘light-for-dates', fetal distress in labour was seen in 24% and 15% were delivered by caesarean section. There was an increased incidence of involuntary infertility and spontaneous abortion. The treatment by prophylactic blood transfusions is discussed.

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