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Amniotic fluid phosphatidylglycerol: an early indicator of fetal lung maturity
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1983.tb08897.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 2, pages 134–138, February 1983
Additional Information
How to Cite
WHITTLE, M. J., WILSON, A. I. and WHITFIELD, C. R. (1983), Amniotic fluid phosphatidylglycerol: an early indicator of fetal lung maturity. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 134–138. doi: 10.1111/j.1471-0528.1983.tb08897.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 5 April 1982 Accepted 10 September 1982
- Abstract
- References
- Cited By
Summary. In a study of 766 amniotic fluids, collected from pregnancies between 26 weeks and term, phosphatidylglycerol (PG) was identified in a greater proportion than was a mature lecithin/sphingomyelin (L/S) ratio at all gestational ages between 28 and 38 weeks regardless of the underlying pregnancy complication. The early appearance of PG was particularly striking in amniotic fluids obtained after preterm rupture of membranes.
Since PG has been previously shown to be a useful indicator of the risk of neonatal respiratory distress syndrome, its appearance before a mature L/S ratio suggests that its detection offers a considerable advantage in the management of high-risk obstetric problems in which the earliest possible indication that the fetal lungs are mature is required.