Christian Albrechts University, Kiel, Federal Republic of Germany.
Langerhans’cells in human cervical epithelium: an immunohistological study
Article first published online: 23 AUG 2005
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 5, pages 400–411, May 1983
How to Cite
MORRIS, H. H. B., GATTER, K. C., STEIN, H. and MASON, D. Y. (1983), Langerhans’cells in human cervical epithelium: an immunohistological study. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 400–411. doi: 10.1111/j.1471-0528.1983.tb08935.x
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 17 August 1982 Accepted28 October 1982
Summary. Langerhans’cells are intraepithelial dendritic cells believed to be important in the recognition and processing of exogenous antigens. They were demonstrated by immunohistological methods in cervical tissue obtained from 10 subjects ranging in age from 30 weeks gestational age to 62 years. Langerhans’cells were clearly delineated in all tissue sections and appear to form a relatively constant component of both the transformation zone and ectocervical epithelium. In addition to Langerhans’cells, a population of T lymphocytes characterized as predominantly T-cytotoxic/suppressor cells have also been demonstrated. The interaction between Langerhans’cells, T lymphocytes and stromal macrophages and their relation to antigen recognition is discussed.