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Absence of a factor blocking a cellular cytotoxicity reaction in the serum of women with recurrent abortions
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1983.tb08943.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 90, Issue 5, pages 453–456, May 1983
Additional Information
How to Cite
FIZET, D. and BOUSQUET, J. (1983), Absence of a factor blocking a cellular cytotoxicity reaction in the serum of women with recurrent abortions. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 453–456. doi: 10.1111/j.1471-0528.1983.tb08943.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 26 April 1982 Accepted 5 December 1982
- Abstract
- References
- Cited By
Summary. The serum of pregnant women contains a non-specific immuno-suppressive factor able to block an in vitro cellular cytotoxicity reaction. This activity increases during the first trimester and persists for 3 months after delivery. The factor is active in dilution. Ten women who had recurrent abortions were typed for HLA antigens and were found to share several antigens with their husband. In all these women, the‘blocking factor’was absent from their serum. The absence of the‘blocking factor’could be used as a clinical test to predict spontaneous abortion.