Luteinizing hormone releasing hormone analogue in treatment of hypergonadotrophic amenorrhoea

  1. V. MENON Research Registrar1,
  2. R. LOGAN EDWARDS Consultant Gynaecologist2,
  3. S. S. LYNCH Principal Biochemist1,
  4. W. R. BUTT Professor of Endocrinology1

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1983.tb08964.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 90, Issue 6, pages 539–542, June 1983

Additional Information

How to Cite

MENON, V., EDWARDS, R. L., LYNCH, S. S. and BUTT, W. R. (1983), Luteinizing hormone releasing hormone analogue in treatment of hypergonadotrophic amenorrhoea. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 539–542. doi: 10.1111/j.1471-0528.1983.tb08964.x

Author Information

  1. 1

    Department of Clinical Endocrinology, Birmingham and Midland Hospital for Women, Sparkhill, Birmingham B11 4HL, UK

  2. 2

    Department of Obstetrics and Gynaecology, Birmingham and Midland Hospital for Women, Sparkhill, Birmingham B11 4HL, UK

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 27 July 1982 Accepted 10 November 1982

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Summary. The effect of a luteinizing hormone releasing hormone analogue (HOE 766) was studied in four patients with hypergonadotrophic amenorrhoea (resistant ovary syndrome). After an initial phase of stimulation, there was a uniform and sustained suppression of gonadotrophin concentrations in all the patients during the 20–24 days of treatment, presumably due to down-regulation of the pituitary receptors. One patient ovulated after stopping treatment.

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