Smoking habits and maternal serum a-fetoprotein levels during the second trimester of pregnancy

  1. STEN G. THOMSEN1,
  2. LENNARTISAGER SALLY1,
  3. AKSEL P. LANGE1,
  4. NINA SAURBREY1,
  5. VIBEKE SCHIOLIER2

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1983.tb09300.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 90, Issue 8, pages 716–717, August 1983

Additional Information

How to Cite

THOMSEN, S. G., SALLY, L., LANGE, A. P., SAURBREY, N. and SCHIOLIER, V. (1983), Smoking habits and maternal serum a-fetoprotein levels during the second trimester of pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 716–717. doi: 10.1111/j.1471-0528.1983.tb09300.x

Author Information

  1. 1

    Department of Obstetrics and Gynaecology, Herlev University Hospital, Herlev Ringvej, DK–2730 Herlev, Denmark

  2. 2

    Department of Clinical Chemistry, Herlev University Hospital, Herlev Ringvej, DK–2730 Herlev, Denmark

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 10 January 1983 Accepted 5 May 1983

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Summary. In a prospective study the influence of cigarette smoking on maternal serum a-fetoprotein levels at 16 weeks gestation was examined. Significantly higher levels were found in 120 smokers compared with 138 non-smokers (median 54.0 and 44.3 μg/1 respectively, P<0.001). No difference in maternal body weight between the two groups could account for the results. The possibility of smoking-induced increased permeability of the placental barrier is discussed.

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