Can the fetus regulate its calcium uptake?

  1. TAPIO KUOPPALA1,*,
  2. RISTO TUIMALA2,
  3. MARKKU PARVIAINEN3,
  4. TIMO KOSKINEN3

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1984.tb04736.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 91, Issue 12, pages 1192–1196, December 1984

Additional Information

How to Cite

KUOPPALA, T., TUIMALA, R., PARVIAINEN, M. and KOSKINEN, T. (1984), Can the fetus regulate its calcium uptake?. BJOG: An International Journal of Obstetrics & Gynaecology, 91: 1192–1196. doi: 10.1111/j.1471-0528.1984.tb04736.x

Author Information

  1. 1

    Department of Obstetrics and Gynaecology, Oulu University Central Hospital, Finland

  2. 2

    Department of Obstetrics and Gynaecology, Tampere University Central Hospital, Finland

  3. 3

    Department of Clinical Sciences, University of Tampere, Finland

* T. Kuoppala, Department of Obstetrics and Gynaecology, Oulu University Central Hospital, SF-90220 Oulu, Finland.

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 6 December 1983; Accepted 5 April 1984

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Summary. To investigate the role of the fetus in vitamin D metabolism concentrations of vitamin D metabolites, 25(OH)D, 24,25(OH)2D and 1,25(OH)2D, were measured in human umbilical artery and vein. There were no differences between artery and vein in 25(OH)D and 24,25(OH)2D levels. 1,25(OH)2D concentrations were statistically significantly higher in the artery than in the vein. It has been shown in animal experiments that 1,25(OH)2D is an important factor in the maintenance of the placental calcium gradient. We suggest that the fetus actively produces 1,25(OH)2D and hence has the capacity to control its calcium influx.

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