Deceased, 11 February 1983
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Prostaglandins in menstrual fluid in menorrhagia and dysmenorrhoea
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1984.tb04829.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 91, Issue 7, pages 673–680, July 1984
Additional Information
How to Cite
REES, M. C. P., ANDERSON, A. B. M., DEMERS, L. M. and TURNBULL, A. C. (1984), Prostaglandins in menstrual fluid in menorrhagia and dysmenorrhoea. BJOG: An International Journal of Obstetrics & Gynaecology, 91: 673–680. doi: 10.1111/j.1471-0528.1984.tb04829.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 11 July 1983 Accepted 22 October 1983
- Abstract
- References
- Cited By
Summary.
Menstrual fluid was collected in vaginal cups inserted for 2 h during the first 2 days of menstruation and menstrual serum concentrations of prostaglandins PGF2α and PGE2 were measured by radio-immunoassay. In 16 women from whom menstrual fluid was collected on both days, PGF2α and PGE2 concentrations were significantly higher on day 1 than on day 2. The highest concentrations of PGF 2α and PGE2 were found in dysmenorrhoeic women on day 1. In non-dysmenorrhoeic women, the amount of PGF2α and PGE2 collected in 2 h correlated directly with total menstrual blood loss. There was no statistically significant difference in the amount of prostaglandins collected in 2 h in pain-free menorrhagic women and dysmenorrhoeic women with normal loss. There was also no significant 9-ketoreductase or 9-hydroxydehydro-genase activity present in menstrual fluid which could suggest PGE2 to PGF2α interconversion.