Present position: Senior Registrar in Obstetrics and Gynaecology, Queen's Medical Centre, Nottingham.
1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
The fetal renin-angiotensin system in pregnancy-induced hypertension
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1984.tb05270.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 91, Issue 1, pages 3–6, January 1984
Additional Information
How to Cite
SYMONDS, E. M., LAMMING, G.D. and CRAVEN, D.J. (1984), The fetal renin-angiotensin system in pregnancy-induced hypertension. BJOG: An International Journal of Obstetrics & Gynaecology, 91: 3–6. doi: 10.1111/j.1471-0528.1984.tb05270.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 1 February 1983; Accepted 15 June 1983
- Abstract
- References
- Cited By
Summary. Maternal and fetal blood samples were obtained from 10 normotensive primigravidae and 10 primigravidae with pregnancies complicated by hypertension and proteinuria. Measurements were performed of plasma renin activity (PRA), plasma renin concentration (PRC) and plasma renin substrate (PRS). PRA and PRC were significantly higher in cord artery and cord vein blood than in maternal venous blood in normotensive women, and PRS was significantly lower. PRS levels were lower in maternal plasma of hypertensive women and, although PRC and PRA were lower in the cord blood of infants born to hypertensive women, these differences did not achieve statistical significance.