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Changes in serum uric acid concentrations during normal pregnancy
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1984.tb05895.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 91, Issue 2, pages 128–132, February 1984
Additional Information
How to Cite
LIND, T., GODFREY, K. A., OTUN, H. and PHILIPS, P. R. (1984), Changes in serum uric acid concentrations during normal pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 91: 128–132. doi: 10.1111/j.1471-0528.1984.tb05895.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 28 March 1983; Accepted 5 May 1983
- Abstract
- References
- Cited By
summary
Serial changes in serum uric acid concentrations have been studied in a group of healthy women before conception, at regular intervals throughout pregnancy and finally 12 weeks afterdelivery. Compared with pre-pregnancy values uric acid concentrations decreased significantly by 8 weeks gestation and this reduced level was maintained until about 24 weeks. Thereafter the concentrations increased such that by term they were greater than the pre-pregnancy values in the majority of patients and remained elevated until at least 12 weeks after delivery. If clinical management during the second half of pregnancy is to be based on increases in serum uric acid concentrations then such increases will have to be carefully interpreted against the background of rising concentrations which occur as part of the physiological response to normal pregnancy.