Human placental lactogen in pre-eclampsia

  1. B. C. OBIEKWE1,*,
  2. D. STURDEE2,
  3. B. L. COCKRILL3,
  4. T. CHARD1

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1984.tb15079.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 91, Issue 11, pages 1077–1080, November 1984

Additional Information

How to Cite

OBIEKWE, B. C., STURDEE, D., COCKRILL, B. L. and CHARD, T. (1984), Human placental lactogen in pre-eclampsia. BJOG: An International Journal of Obstetrics & Gynaecology, 91: 1077–1080. doi: 10.1111/j.1471-0528.1984.tb15079.x

Author Information

  1. 1

    Department of Obstetrics and Gynaecology, and Reproductive Physiology, St Bartholomew's Hospital Medical College and The London Hospital Medical College

  2. 2

    Department of Obstetrics and Gynaecology, Solihull Hospital

  3. 3

    Department of Clinical Chemistry, Solihull Hospital

* B. C. Obiekwe, Department of Obstetrics and Gynaecology, St Bartholomew's Hospital Medical School, West Smithfield, London EC1A 7BE.

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 24 June 1983 Accepted 30 April 1984

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Summary. Serum placental lactogen (hPL) was measured in serial blood samples obtained from 663 pregnant women at weekly intervals from 36 to 40 weeks. The group included 231 women with pre-eclampsia. Levels of hPL were significantly elevated in primigravidae with this condition but not in multigravidae. In all groups hPL levels were significantly reduced in association with growth retardation, but the clinical value of this observation appeared to be greater in multigravidae than in primigravidae. It is suggested that in primigravidae with pre-eclampsia maternal hPL levels reflect both the pathology of the disease as well as the condition of the fetus.

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