The significance of anti-c alloimmunization in pregnancy
Article first published online: 22 AUG 2005
DOI: 10.1111/j.1471-0528.1986.tb07829.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 93, Issue 10, pages 1044–1048, October 1986
Additional Information
How to Cite
BOWELL, P. J., BROWN, S. E., DIKE, A. E. and INSKIP, M. J. (1986), The significance of anti-c alloimmunization in pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 93: 1044–1048. doi: 10.1111/j.1471-0528.1986.tb07829.x
Publication History
- Issue published online: 22 AUG 2005
- Article first published online: 22 AUG 2005
- Received 12 May 1986, Accepted 15 June I986
- Abstract
- References
- Cited By
Summary. In an 8-year period, 177 of 280 000 pregnancies were complicated by maternal anti-c alloimmunization. Although there was one neonatal death associated with anti-c haemolytic disease of the newborn, only two infants were severely anaemic at birth. A total of 11 babies required exchange transfusion, but nine of these developed hyperbilirubinaemia alone. The remaining c positive infants were either unaffected or only mildly affected by erythroblastosisfetalis. A strategy for management of these pregnancies is outlined, and proposed methods of prevention and serological control are discussed.

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