1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
Intracellular binding proteins for retinol and retinoic acid in early and term human placentas
Article first published online: 22 AUG 2005
DOI: 10.1111/j.1471-0528.1986.tb07991.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 93, Issue 8, pages 833–838, August 1986
Additional Information
How to Cite
GREEN, T. and FORD, H. C. (1986), Intracellular binding proteins for retinol and retinoic acid in early and term human placentas. BJOG: An International Journal of Obstetrics & Gynaecology, 93: 833–838. doi: 10.1111/j.1471-0528.1986.tb07991.x
Publication History
- Issue published online: 22 AUG 2005
- Article first published online: 22 AUG 2005
- Received 6 August 1985, Accepted 18 February 1986
- Abstract
- References
- Cited By
Summary. Specific binding of both [3H]retinol and [3H]retinoic acid was observed in the cytosol fraction from term placentas and specific binding of [3H]retinol but not [3H] retinoic acid was detected in the cytosol fraction from placentas of 8–12 week pregnancies. The elution volume of the bound radioactivity on Sephadex G-100 column chromatography was within the range expected for proteins of molecular weight 14500, in agreement with the results of others for cellular retinol-and retinoic acid-binding proteins from other tissues. The role of these proteins in mediating the effects of vitamin A on growth and differentiation of the placenta and fetus has yet to be determined.