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Fertility and pregnancy after operation for a prolactinoma

  1. AMANDA M. RICHARDS Registrar in Obstetrics and Gynaecology1,
  2. M. R. R. BULLOCK Neurosurgical Registrar2,
  3. G. M. TEASDALE Professor of Neurosurgery2,*,
  4. J. A. THOMSON Reader in Medicine3,
  5. M. I. KHAN Medical Student4

Article first published online: 23 AUG 2005

DOI: 10.1111/j.1471-0528.1986.tb08660.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 93, Issue 5, pages 495–502, May 1986

Additional Information

How to Cite

RICHARDS, A. M., BULLOCK, M. R. R., TEASDALE, G. M., THOMSON, J. A. and KHAN, M. I. (1986), Fertility and pregnancy after operation for a prolactinoma. BJOG: An International Journal of Obstetrics & Gynaecology, 93: 495–502. doi: 10.1111/j.1471-0528.1986.tb08660.x

Author Information

  1. 1

    University Department of Obstetrics and Gynaecology, Glasgow Royal Infirmary

  2. 2

    Department of Neurosurgery, Institute of Neurological Sciences, Glasgow G51 4TE

  3. 3

    Consultant Endocrinologist, University Department of Medicine, Glasgow Royal Infirmary

  4. 4

    Department of Neurosurgery, Institute of Neurological Sciences, Glasgow G51 4TF

* Professor G. M. Teasdale Department of Neurosurgery, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF

Publication History

  1. Issue published online: 23 AUG 2005
  2. Article first published online: 23 AUG 2005
  3. Received 2 November 1984 Accepted 10 July 198s.

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Summary. Pituitary exploration was performed in 40 women with hyperprolactinaemic infertility and a prolactinoma was found in 37. After operation 26 (65%) of the 40 patients had a normal serum prolactin concentration; 31 women have so far had 49 pregnancies; in seven of these patients bromocriptine therapy was used after surgery. Eight of the remaining nine women were shown to be ovulating, but four of these subsequently decided not to attempt a pregnancy. The course and outcome of the 49 pregnancies were similar to those in normal women and no visual or endocrine complications occurred. Surgical removal of a prolactinoma often restores fertility, and may secure a safer pregnancy.

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