Medical dilatation of the non-pregnant cervix: the effect of ethinyl oestradiol on the visibility of the transformation zone
Article first published online: 23 AUG 2005
DOI: 10.1111/j.1471-0528.1986.tb08662.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 93, Issue 5, pages 508–511, May 1986
Additional Information
How to Cite
PRENDIVILLE, W. J., DAVIES, W. A. R., DAVIES, J. O. and SHEPHERD, A. M. (1986), Medical dilatation of the non-pregnant cervix: the effect of ethinyl oestradiol on the visibility of the transformation zone. BJOG: An International Journal of Obstetrics & Gynaecology, 93: 508–511. doi: 10.1111/j.1471-0528.1986.tb08662.x
Publication History
- Issue published online: 23 AUG 2005
- Article first published online: 23 AUG 2005
- Received 21 January I985 Accepted 18 June 1985
- Abstract
- References
- Cited By
Summary. The cervical transformation zone (TZ) was not fully visible in 25 women referred to the colposcopy clinic with cytological suspicion of cervical intraepithelial neoplasia (CIN). Each was given a 5-day course of oral ethinyl oestradiol during the follicular phase of the menstrual cycle, and colposcopy was then repeated. The transformation zone was visible at this second examination in 16 of the 25 patients. Of these patients, 11 were treated with a local destructive technique, nine by laser, two by cryocautery; one patient had a cone biopsy, and four patients did not require treatment. Although cone biopsy was necessary in 8 of the remaining 9 patients it is encouraging that the use of a simple medical regimen allowed us to avoid conisation and its morbidity in almost two thirds of these patients.

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