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Choice of oxytocic preparation for routine use in the management of the third stage of labour: an overview of the evidence from controlled trials
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1988.tb06476.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 95, Issue 1, pages 17–30, January 1988
Additional Information
How to Cite
ELBOURNC, D., CHALMERS, I. and PRENDIVILLE, W. (1988), Choice of oxytocic preparation for routine use in the management of the third stage of labour: an overview of the evidence from controlled trials. BJOG: An International Journal of Obstetrics & Gynaecology, 95: 17–30. doi: 10.1111/j.1471-0528.1988.tb06476.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 18 May 1987, Accepted 23 July 1987
- Abstract
- References
- Cited By
Summary. Prophylactic use of oxytocics reduces the risk of postpartum haemorrhage by about 40%. The analysis presented in this paper assesses which oxytocic preparation is associated with the least risk of postpartum haemorrhage and examines the relative effects of different preparations on the length of the third stage, the risk of manual removal of the placenta, blood pressure and other side-effects. A mixture of oxytocin and ergometrine (Syntometrine) appears to be the safest and most effective prophylactic of the alternatives which have been compared, but the quality of the evidence is not satisfactory. There is scope for a randomized comparison of Syntometrine with oxytocin to obtain unbiased and more precise estimates of their relative effects on postpartum haemorrhage, blood pressure and unpleasant side-effects.