1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
Bone histology and mineral homeostasis in human pregnancy
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1988.tb06568.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 95, Issue 9, pages 849–854, September 1988
Additional Information
How to Cite
PURDIE, D. W., AARON, J. E. and SELBY, P. L. (1988), Bone histology and mineral homeostasis in human pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 95: 849–854. doi: 10.1111/j.1471-0528.1988.tb06568.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Submitted 24 February 1987, Resubmitted 18 January 1988, Accepted 10 April 1988
- Abstract
- References
- Cited By
Summary. Mineral homeostasis was studied biochemically and histologically in patients in early pregnancy and at term. In early pregnancy there was evidence of increased and reversible resorption of bone, whereas in late pregnancy bone demonstrated active formation and rapid mineralization with minimal resorption. Gut absorption of calcium was not increased in early pregnancy. The overall findings were consistent with calcium liberation from bone in early pregnancy, and with enhanced conservation of bone calcium at term. It is proposed that the additional calcium required during pregnancy is derived largely from the skeleton during early gestation and from dietary absorption at term.