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The variation in cervical hydroxyproline and cervical water with age
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1988.tb06794.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 95, Issue 11, pages 1159–1164, November 1988
Additional Information
How to Cite
ROBERTS, A. D. G., CORDINER, J. W., HART, D. M., BARLOW, D. H., MacRAE, D. and LEGGATE, I. (1988), The variation in cervical hydroxyproline and cervical water with age. BJOG: An International Journal of Obstetrics & Gynaecology, 95: 1159–1164. doi: 10.1111/j.1471-0528.1988.tb06794.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 20 July 1987, Accepted 9 May 1988
- Abstract
- References
- Cited By
Summary. The squamocolumnar junction is frequently not visible in the postmenopausal patient. This study attempts to identify some of the changes in the cervix that may account for this observation. Twentyfour cervical biopsy samples taken at the squamocolumnar junction were analysed for hydroxyproline (collagen) and water content. There was significantly more hydroxyproline (collagen) in the premenopausal woman than the postmenopausal woman. Similarly, there was higher percentage of water in the biopsies in the premenopausal woman than the postmenopausal woman. Further samples obtained deeper in the cervical stroma did not confirm these differences. It appears likely that differences in cervical water and cervical collagen near the surface of the cervix account, at least in part, for the lack of visibility of the squamocolumnar junction in the older woman.