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Summary. The effect of magnesium supplementation in pregnancy was studied in 568 women who were treated with 15 mmol magnesiumaspartate-hydrochloride per day or aspartic acid as placebo given orally during pregnancy from leqslant R: less-than-or-eq, slant16 weeks. Allocation to the two groups was performed according to the women's birthdates. Magnesium supplementation during pregnancy was associated with significantly fewer maternal hospitalizations, a reduction in preterm delivery, and less frequent referral of the newborn to the neonatal intensive care unit. The results suggest that magnesium supplementation during pregnancy has a significant influence on fetal and maternal morbidity both before and after delivery.