Phenytoin sodium and magnesium sulphate in the management of eclampsia
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1990.tb01734.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 97, Issue 2, pages 104–109, February 1990
Additional Information
How to Cite
DOMMISSE, J. (1990), Phenytoin sodium and magnesium sulphate in the management of eclampsia. BJOG: An International Journal of Obstetrics & Gynaecology, 97: 104–109. doi: 10.1111/j.1471-0528.1990.tb01734.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 19 May 1989 Accepted 5 September 1989
- Abstract
- References
- Cited By
Summary. Twenty-two patients with eclampsia were randomly allocated to receive either intravenous phenytoin sodium or intravenous magnesium sulphate. The groups were comparable. No side-effects occurred and therapeutic levels were obtained in both groups. While none of the 11 patients managed with magnesium sulphate had further convulsions, four of the 11 treated with phenytoin sodium did and were subsequently effectively treated with magnesium sulphate. These results suggest that phenytoin sodium is not as effective an anticonvulsant in eclampsia as is magnesium sulphate.

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